Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. There are lots of chemical agents available to control and to treat diabetic patients, but total recovery from diabetes has not been reported up to this date. Alternative to these synthetic agents, plants provide a potential source of hypoglycaemic drugs and are widely used in several traditional systems of medicine. Helicteres isora has been documented as a traditional treatment of diabetes. The effect of this plant may delay the development of diabetic complications and correct the metabolic abnormalities using variety of mechanisms. This research focuses mainly on the hypoglycemic activity of various extracts of dried fruits of H. isora in alloxan induced hyperglycemia and increased the glucose uptake in rat diaphragm.
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